Eric Asselin, PhD

13 Oct 2017

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Research interests

  • Uterine and ovarian biology, physiology and endocrinology
  • Hormone-dependent cancers of the female reproductive system
  • Animal models and transgenesis

Dr. Asselin’s research laboratory is interested understanding the regulation of cell survival and cell death in the context of embryo implantation, endometrial decidualization and in pathological conditions such as chemoresistance in gynecological cancers (endometrial and ovarian). More precisely, his laboratory has been actively investigating the PI-3K/Akt pathway in this context. Animal models, transgenic mouse human biopsies, cell lines are used in his laboratory to study this signaling pathway at the cellular and molecular level. His laboratory include 4 PhD students and 2 MSc students. For the last 24 years, he has trained more than 85 undergraduate and graduate students and postdoctoral fellows. His group has published more than 98 publications in peer-review international scientific journals, with a citation impact factor of 49 (H factor, goggle scholar). He was recipient of a FRQS chercheur-boursier, a CIHR New Investigator Award and the Canada Research Chair in Molecular Gyneco-oncology from 2006 to 2016.

Members of the laboratory

Jasmine Nolan
Undergraduate trainee

Kelliane Béland
Undergraduate trainee

Maélla Darina Ankely Kengni
MSc student

Raphaëlle Proulx
MSc student

Pascal Adam, MSc
PhD student
pascal.adam@uqtr.ca

Junie Chansi, MSc
PhD student
junye3@gmail.com

Emna Bouaine
PhD student

Léa-Isabelle Renaud
PhD student

Publications

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Derek Boerboom, DVM, PhD

11 Jun 2016

Address

Research interests

  • Roles of developmental signaling pathways in gonadal physiology
  • Cancers of the reproductive system
  • Transgenesis and functional genomics

Our primary field of interest is the role played by developmental signaling pathways in the functioning of the ovary. Pathways such as Wnt, Hippo and Slit/Robo are best known for their critical roles in a variety of tissues and cell types during embryonic development. It has become apparent, however, that these “developmental” pathways are also active in adult life, and their roles in this context are only beginning to become known. Using a functional genomics approach, our group has shown that the Wnt pathway is a key player in the ovary, acting downstream of the gonadotropins to regulate follicle survival, growth and ovulation. Current research projects are also examining the role of Hippo signaling in ovary and testis, as well as in the development of different cancers of the reproductive system, including the ovary, uterus and mammary gland.

Members of the laboratory

Florine Grudet, BSc
PhD student
florine.grudet@umontreal.ca

Philippe Godin, DVM
PhD student
phil.godin0934@gmail.com

Michael Bérubé
DVM/PhD student
michael.berube@umontreal.ca

Francis Marien-Bourgeois
Lab technician
francis.marien-bourgeois@umontreal.ca

Publications

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