Julie Hussin, PhD
Assistant professor, Université de Montréal
We use genomic and clinical data to study the causes of reproductive challenges in human, and identify key biological players interacting at all stages in the reproduction process. Our main focus is to mine genomes of individuals in populations with detailed fertility phenotypes and rich environmental metrics. Understanding the genomics of fertility and its interactions is an essential step towards improving diagnosis, solutions and prevention in fertility-challenged populations.
In both women and men, many links have been made between fertility and cardiovascular conditions. To name a few, sterile men are more likely to suffer from heart disease and women with cardiovascular conditions have an increase risk of pregnancy complications, while obesity is a risk factor affecting both male and female fertility.
More fundamentally, we are highly interested in meiosis, the specialized cell division at the heart of reproductive genetics. Our interests include meiotic recombination, the meosis-regulator PRDM9 and sex chromosome dynamics and evolution. Specifically, we study sex chromosomes in a very important model organism for meiosis research, Ornithorhynchus anatinus (platypus) to gain insights into mammalian evolution processes.