Werner Giehl Glanzner, DVM, MSc, PhD

Assistant professor, McGill University

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Address

Research interests

  • Biotechnology and embryo development
  • Embryo epigenetic and molecular regulation
  • Gene and epigenome editing

Epigenetic regulation of early embryo development:
Epigenetic regulation has a vital role for successful embryo development regulating aspects related to embryo genome activation and cell lineage specification. Our research aims to unravel the epigenetic regulators that participate control the embryo outcomes. Nevertheless, we are also focused in understanding the connection between epigenetics and metabolic and oxidative status during early embryo development.

miRNAs and DNA methylation and its connection with oocyte to embryo transition (OET)
The role of miRNAs and DNA methylation in promoting the OET and the interconnection with other epigenetic regulators are not clearly understood. Therefore, we aim to explore the connection between miRNAs and DNA methylation with epigenetic regulators that together contribute to the embryo genome activation and transcriptional activity during early embryo development.

Genome and epigenome editing
Our lab is using gene and epigenome editing tools for generation of animal models for both biomedical field and agricultural purposes. The animal models include the pig and non-human primates, more specifically the Common marmoset.

Members of the laboratory

Liam Socransky
MSc student
liam.socransky@mail.mcgill.ca

Sabrina Roy
Honours student
sabrina.roy2@mail.mcgill.ca

Publications